Chemoradiotherapy for Early-stage Nasopharyngeal Disease - The ASCO Post

Given the better outcomes of Stage III and IV NPC on CCRT, one wonders if the same radiosensitising effect would benefit the earlier stages.

Stage I and IIa NPC has up to now never been candidates for concurrent chemotherapy, since outcomes have been good on radiotherapy alone.

This trial addresses that particular gap in our knowledge and the results suggest that the benefit is not only significant, it is a worthwhile endeavor given the minimal and controllable adverse effects.

http://www.ascopost.com/articles/january-15-2012/chemoradiotherapy-for-early-stage-nasopharyngeal-disease/

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