What's useful about this simple descriptive study is that it represents a closer-to-home Asian profile, and a stratification into 3 equal groups of young/middle-aged/elderly men for comparison.
What the demonstrates is that OSA decreases in severity and CSA increases with age!
The questions this raises is:
1- What physiologic mechanisms are at work to reduce upper airway obstruction and inhibit respiratory drive?
2- What does this mean for long-term follow up? Should we retest and how often to see this reduction, potentially reversal of OSA?
3- How does this change management strategies? Is there a role for weaning off CPAP (given the poor compliance rates, long term) and exploring surgical modalities as age advances? (I can see how this is important so that patients, given something to look forward to are not lost on follow up).
http://www.ncbi.nlm.nih.gov/m/pubmed/22276350/
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Q1: Skin Lesion
15 years ago
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